Immune dysregulation is a form of excessive response of the immune system with various manifestations, such as recurrent fever, hyperinflammation, rheumatologic diseases, autoimmune diseases or lymphoproliferation. It is increasingly identified in patients and is seen not only in rheumatology and clinical immunology units, but also in other specialties due to the tendency for multiple organ and system involvement.

Thanks to recent scientific advances, affected patients now have more options for diagnosis of the underlying immunopathology, as well as for treatment, with the goal of more personalized, targeted and effective management.

This second edition, taught by international leaders in the field, aims to provide the most up-to-date knowledge in the diagnosis and treatment of patients with manifestations of immune dysregulation, from an interdisciplinary perspective, in order to offer them the most optimized management to improve their prognosis and quality of life.

• Pediatricians.
• Rheumatologists.
• Immunologists.
• Hemato-oncologists.
• Nurses.
• Biologists.
• Geneticists.

• To learn the latest developments in the pathophysiology of immune dysregulation and its management, both diagnostically and therapeutically, as well as highlight the importance of reference units.
• To identify the points of collaboration between rheumatologists, clinic and laboratory immunologists in the diagnostic and therapeutic process, and highlight the importance of interdisciplinary management.
• To be updated on the newest diagnostic techniques in immune dysregulation based on genomics, proteomics, and transcriptomicsm and to visualise where biomarker research is heading.
• To define the latest developments in immunomodulation to explain the current therapeutic possibilities, and foresee where research in immunomodulation is heading.

Table 1: Advances in diagnosis in immune dysregulatory diseases

• RNA signatures in clinical practice: Gaps and knowns.
• Validation of variants of uncertain significance.

Table 2: Advances in treatment in immune dysregulatory diseases

• Update in B-cell disturbances in autoimmune diseases.
• Role of T-cell in B-cell autoimmunity.
• CAR-T therapies in autoimmune diseases: Gaps and knowns in efficacy and safety.
• Biomarkers of B cell reservoir in pediatrics to understand the impact of B-cell depleting therapies.
• Allogenic hematopoietic stem cell transplantation in immune dysregulation.
• Gene therapy in immune disorders.

• Free registration.
• Hybrid course: Onsite (SJD Auditorum) and online (webinar).
• The webinar link will be provided 48 hours before the start of the course.
• The link to the recorded course will be sent to registrants after 4-6 weeks.
• We remind you that you will have at your disposal, in the virtual classroom, the satisfaction survey that you will have to fill in in order to obtain your corresponding certificate.

*** If you have any problems with the registration process, please contact hospitalbarcelona.aula@sjd.es and we will help you as soon as possible.