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3rd Immune dysregulation workshop Barcelona: From basics to clinics to advanced therapies

A FOCIS Center of Excellence initiative (CIS-UB) bringing together leading experts to advance immune health

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FOCIS Center of Excellence CIS-UB: Leading Innovation in Immunology

The CIS-UB (Clínic for Immunology along Sant Joan de Déu in University of Barcelona) is a joint initiative bringing together Hospital Sant Joan de Déu Barcelona, Spain’s leading pediatric hospital; Hospital Clínic de Barcelona, a national reference center for adult care; and the University of Barcelona, a top institution in biomedical teaching and research.

This strategic collaboration integrates patient care, research, and education to advance the diagnosis and treatment of immunological diseases in both children and adults. Through shared units and laboratories, the development of advanced therapies, and participation in international networks, CIS-UB strengthens Barcelona’s position as a hub for immunotherapy, transplantation, autoimmune disorders, and immunodeficiencies, while also training the next generation of specialists and researchers.

A strategic alliance

logotipo del Hospital Sant Joan de Déu Barcelona
Logotip Hospital Clínic Barcelona
logotipo de la Universitat de Barcelona
Figura conceptual de un niño con los órganos internos visibles en formato dibujo amable y con color. El fondo y la figura del niño en tonos amarillos.

Shaping the future of Immune Dysregulation

The 3rd Immune Dysregulation Workshop will gather leading international experts in a unique forum to share the latest breakthroughs in understanding, diagnosing, and treating immune dysregulation disorders.

Across three dynamic days, participants will explore advances ranging from the foundations of immune regulation to innovative therapies such as Treg-based strategies, thymic transplantation, gene therapy, CAR-T approaches in pediatric and autoimmune diseases, and new frontiers in GMP-based advanced therapy manufacturing.

An inspiring space where science and clinical innovation converge to transform patient care.

At the end of this training you will be able to:

  • Understand and highlight the most recent advances in immune dysregulation, spanning from basic mechanisms to clinical applications.
  • Explore and discuss innovative therapeutic strategies, including Treg-based approaches, gene therapy, and CAR-T in autoimmune and pediatric diseases.
  • Exchange knowledge and foster collaboration between international clinicians and researchers.
  • Apply practical insights into the development and manufacturing of advanced therapies in GMP settings.

Improve your skills in:

Clinical Assistance ProceduresDecision makingKnowledge and understanding of pathologiesInterpreting resultsDiagnostic skills

Contents:

Wednesday 17th December.

Location: Tau room at CosmoCaixa

Table 1:

Advances in mechanisms underlying immune dysregulatory diseases.

Topic 1
Primary and secondary thymic defects: clinical and immunological phenotype.

Rubén Barricarte, PhD. Vanderbilt University and Hospital Sant Joan de Déu Barcelona.

Topic 2
Impact of thymic damage on early T cell development.

Marieke Lavaert, PhD. National Institute of Allergy and Infectious Diseases, NIH, Bethesda.

Topic 3
Role of IgD in peripheral tolerance.

Andrea Cerutti, MD/PhD. IMIM. Barcelona

Table 2:

Advances in treatment in immune dysregulatory diseases.

Topic 1
Treg-cell based therapies.

Rafael Correa, PhD. Laboratory of Immune-Regulation, Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.

Topic 2
Thymic transplantation.

Alexandra Kreins, MD. University College London, London.

Topic 3
Treg phenotypes in primary immune regulatory disorders and impact of immunomodulatory drugs.

Daniel Acevedo-Gomez, MsC. Hospital Sant Joan de Deu.

Topic 4
Tregs in SLE: Friends or Foes?

Virginia Pascual, MD/PhD. Gale and Ira Drukier Director of Children's Health Research, Weill Cornell Medical College. New York.

Thursday 18th December.

Location: Agora room at CosmoCaixa

Table 3:

Gene therapy and preclinical studies.

Topic 1
Artificial Patient-Specific Human Thymic Organoids for Preclinical Models.

Anna Villa, MD/PhD. San Rafaelle. Milan.

Topic 2
Preclinical development of gene therapy for Major Histocompatibility Complex Class II (MHC II) Deficiency gene therapy.

Alessandra Magnani, MD/PhD. Hospital Sant Joan de Deu. Barcelona.

Topic 3
Vectors for integrative gene therapy. How to develop Lentivirus under GMP rules.

Hugo Calderón, PhD. Hospital Clínic de Barcelona, Barcelona.

Topic 4
Advances in GT for rare diseases: Fanconi and LAD1.

Juan Bueren, PhD. CIEMAT. Madrid.

Table 4:

CAR-T therapies.

Topic 1
Understanding autoimmune disease relapse in B-cell-depleting CAR-T therapy.

Carola García Vinuesa, MD/PhD. The Francis Crick Institute, London.

Topic 2
CAR T cells for paediatric indications: innovation and future prospectives.

Concetta Quintarelli, PhD. Gene Therapy Lab, Ospedale Bambino Gesù, Rome.

Topic 3
CAR-T developments: for preclinical to clinical proposals.

Lorena Perez, PhD. CaixaResearh Institute for Immunology. Barcelona.

Topic 4
Long-term efficacy and safety of CART-19: Barcelona’s experiences.

Julio Delgado, MD/PhD. Hospital Clinic de Barcelona, Barcelona.

Topic 5
Developing CAR-T clinical trials in Autoimmune diseases.

H.U. Scherer, University of Leiden, Leiden.

Friday 19th December. Technical workshop in ATMP manufacturing.

Location: Advanced Therapies Platform SJD-Clinic (Sala Pasteur). SJD Barcelona Children's Hospital

Topic 1
Production of ATMPs in clean rooms. General concepts for developing and working in clean rooms. Structures and rules.

Julio Castaño, PhD & Raquel Cabezon, PhD. Joint Platform for ATMPs HCB-HSJD.

Topic 2
Production of cell therapies. From DCs to TILs and CAR-Ts.

Daniel Benitez, PhD & E. Azucena Gonzalez, PhD. Joint Platform for ATMPs HSJD- HCB.

Image of a doctor in consultation, dressed in a white coat and stethoscope, looking at the camera and smiling.

Aimed at:

  • Physicians (immunologists, pediatricians, hematologists, rheumatologists).
  • Clinical researchers and translational scientists.
  • Laboratory specialists in immunology and advanced therapies.
  • Residents, fellows, and PhD students in related fields.
  • Professionals involved in cell and gene therapy development.

Learning experience

We have designed a complete program, carefully prepared with the participation of expert speakers to guarantee you a high-level training experience.

Location

The workshop will be hosted in two emblematic venues in Barcelona.

December 17th & 18th

Tau and Agora room at CosmoCaixa

CosmoCaixa

Carrer d'Isaac Newton, 26 
Distrito de Sarrià-Sant Gervasi
08022 Barcelona

December 19th

SJD Barcelona Children's Hospital

Passeig Sant Joan de Déu 2, 
08950, Esplugues de Llobregat
Barcelona

Training options

IN-PERSON-3rd Immune dysregulation workshop Barcelona: From basics to clinics to advanced therapies
Dates - 
Registration deadlineUntil
ModalityIn person
LanguageEnglish
Places
60  Places left: 51
ONLINE. 3rd Immune dysregulation workshop Barcelona: From basics to clinics to advanced therapies
Dates - 
Registration deadlineUntil
ModalityOnline
LanguageEnglish
Places
Unlimited

Direction

Director
Laia Alsina Manrique de Lara
Head of the Allergy and Clinical Immunology Department
SJD Barcelona Children’s Hospital
Director
Jordi Antón López
Head of Rheumatology Department
SJD Barcelona Children’s Hospital
Director
Manel Juan Otero
Head of the Immunology Service
Hospital Clínic de Barcelona

With the collaboration of:

Logo La Caixa english

Do you need more information?

Write to us and we’ll answer any questions you may have about the program.

Training Administration Office

Sant Joan de Déu Education C. Díaz de la Fuente, 1. 08950 Esplugues de Llobregat (Barcelona)
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